Pharmacokinetics of Digoxin and Derivatives

In the absence of sensitive analytical methods, estimation of the quantity of glycoside in the myocardium was at one time possible only by observing the pharmacologic effect in the intact animal, or in a heart—lung preparation, or in the embryonic chick heart

N. Rietbrock

2012

Scholarcy highlights

  • In the absence of sensitive analytical methods, estimation of the quantity of glycoside in the myocardium was at one time possible only by observing the pharmacologic effect in the intact animal, or in a heart—lung preparation, or in the embryonic chick heart
  • The main disadvantage of the foregoing methods is the relatively low sensitivity

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