Taxol Producing Fungi

Paclitaxel, a diterpenoid natural product, has emerged as a widely used anticancer drug with its unique mode of action and efficacy against multiple forms of cancers

Xiaoran Hao

2013

Scholarcy highlights

  • Paclitaxel, a diterpenoid natural product, has emerged as a widely used anticancer drug with its unique mode of action and efficacy against multiple forms of cancers
  • One of the promising strategies is the use of fungal fermentation for Taxol production
  • This chapter summarizes the recent advances on the study of Taxol-producing fungi, including its taxonomical diversity of the identified strains, the methods for characterization of fungal Taxol, and the molecular basis and heterogenous biosynthesis of Taxol
  • Current problems delaying fungal production of Taxol in industry were discussed

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