Strategies to assess oxidative stress

In order to ascertain the validity and significance of oxidative stress in biological reactions, it is essential to characterize and quantitate the various substances and enzymes in this balance between oxidants and antioxidants

A. Z. Reznick; L. Packer; C. K. Sen

2011

Scholarcy highlights

  • In order to ascertain the validity and significance of oxidative stress in biological reactions, it is essential to characterize and quantitate the various substances and enzymes in this balance between oxidants and antioxidants
  • While oxygen is vital to the existence of all aerobic organisms, under certain circumstances it forms reactive species and derivative oxidants that are noxious to biological molecules
  • An imbalance between oxidant insult and antioxidant defences in favor of the former constitutes the basis for oxidative stress and for conditions leading towards oxidative injury
  • The strategies and methodologies currently available to tackle such issues are reviewed in the present work

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