Symbiotic Origin of Apoptosis

The progress of evolutionary biology has revealed that symbiosis played a basic role in the evolution of complex eukaryotic organisms, including humans

Szymon Kaczanowski

2020

Scholarcy highlights

  • The progress of evolutionary biology has revealed that symbiosis played a basic role in the evolution of complex eukaryotic organisms, including humans
  • Mitochondria are simplified endosymbiotic bacteria currently playing the role of cellular organelles
  • Mitochondrial domestication occurred at the very beginning of eukaryotic evolution
  • Mechanisms of apoptotic programmed cell death exist even in the unicellular organisms, and they play a basic role in the development of complex multicellular organisms, such as fungi, green plants, and animals
  • Regulated cell death is initiated by many different parallel biochemical pathways
  • Our group showed that perturbations of apoptosis in yeasts cause perturbations of oxidative respiration

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