Musso, R., DiLauro, R., Adhya, S., and de Crombrugghe, B., 1977, Dual control for transcription of the galactose operon by cyclic AMP and its receptor protein at two interdispersed promoters, Cell12: 847.PubMedCrossRefGoogle Scholar
2013
Key concepts
Scholarcy highlights
- Musso, R., DiLauro, R., Adhya, S., and de Crombrugghe, B., 1977, Dual control for transcription of the galactose operon by cyclic AMP and its receptor protein at two interdispersed promoters, Cell12: 847.PubMedCrossRefGoogle Scholar
- In bacteria the effects of Cyclic AMP are mediated by the cAMP receptor protein
- Our aim in this article is to address the question: How does CRP activate transcription in bacterial cells? A detailed examination of the mode of action of CRP should help us understand better the mechanisms which govern the activation of genes in prokaryotes, and may provide a conceptual framework in discussions on the role of activators of transcription in eukaryotes
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