Lucigenin (Bis-N-methylacridinium) as a Mediator of Superoxide Anion Production

Lucigenin has frequently been used for the luminescent detection of O−2

Stefan I. Liochev; Irwin Fridovich

2002

Scholarcy highlights

  • Lucigenin has frequently been used for the luminescent detection of O−2
  • The pathway leading to this luminescence requires univalent reduction of Luc2+to LucH+followed by formation of an unstable dioxetane by reaction of LucH+with O−2
  • (2871AR2), the U.S Army Medical Research, and the National Institutes of Health

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