Pyrazolo[1,5-a]Pyrimidine Derivative as Precursor for Some Novel Pyrazolo[1,5-a]Pyrimidines and Tetraheterocyclic Compounds

The 2-(cyanomethyl)-5,7-dimethylpyrazolo pyrimidine-3-carbonitrile 3 reacted with phenyl isothiocyanate to afford the respective thioanilide derivative 4 that is a novel compound that has been unreported hitherto. The latter was used as a precursor to synthesize several novel polyheterocyclic compounds 9, 12, 15, and 19

Nadia Hanafy Metwally; Magda Ahmed Abdallah; Selima Ali Almabrook

2016

Scholarcy highlights

  • The 2-(cyanomethyl)-5,7-dimethylpyrazolopyrimidine-3-carbonitrile 3 reacted with phenyl isothiocyanate to afford the respective thioanilide derivative 4 that is a novel compound that has been unreported hitherto. The latter was used as a precursor to synthesize several novel polyheterocyclic compounds 9, 12, 15, and 19
  • The structures of all the newly synthesized compounds were confirmed on basis of their elemental, spectral data, and plausible mechanism has been postulated to account for their formation
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