HAp@GO drug delivery vehicle with dual‐stimuli‐triggered drug release property and efficient synergistic therapy function against cancer

These findings prove the great potential application of the nanocomposites for cancer therapy

Rui Sang; Min Chen; Yuanyi Yang; Yunfei Li; Jiacheng Shi; Yi Deng; Xianchun Chen; Weizhong Yang

2019

Scholarcy highlights

  • Nanoscale hydroxyapatite is an optimal candidate material in biomedical area for its good biocompatibility and bioactivity
  • HAp nanorods are prepared via hydrothermal method and combined with monolayered graphene oxide
  • The drug release property of DOX loaded HAp@GO is demonstrated to be controlled by pH and near-infrared light, which is favorable for cancer therapy. in vitro studies on cancer therapy demonstrate that the combined treatment, compared with either chemotherapy or photothermal therapy alone, has better synergistic therapeutic effect
  • These findings prove the great potential application of the nanocomposites for cancer therapy
  • Any queries should be directed to the corresponding author for the article

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