Association of prothrombin complex concentrate administration and hematoma enlargement in non-vitamin K antagonist oral anticoagulant-related intracerebral hemorrhage

This retrospective cohort study includes individual patient data for 190 patients with NOAC-associated ICH over a 5-year period at 19 departments of neurology across Germany

Stefan T. Gerner

2018

Scholarcy highlights

  • This retrospective cohort study includes individual patient data for 190 patients with NOAC-associated ICH over a 5-year period at 19 departments of neurology across Germany
  • Subanalyses were calculated for blood pressure management and its association with the primary outcome
  • In contrast to blood pressure control, prothrombin complex concentrate administration was not associated with a reduced rate of hematoma enlargement in NOAC-related ICH
  • Our findings support the need of further investigations exploring new hemostatic reversal strategies for patients with factor Xa inhibitor–related ICH
  • For CNS members, you must be signed into childneurologysociety.org to view articles

Need more features? Save interactive summary cards to your Scholarcy Library.