Electro-synthesized PEDOT/glutamate chemically modified electrode: a combination of electrical and biocompatible features

Neural prosthetic devices have been developed that can facilitate the stimulation and recording of electrical activity when implanted in the central nervous system

Jianfei Che; Yinghong Xiao; Xufei Zhu; Xiaojie Sun

2007

Scholarcy highlights

  • Neural prosthetic devices have been developed that can facilitate the stimulation and recording of electrical activity when implanted in the central nervous system
  • Sodium p-toluenesulfonate was chosen as the first dopant and subsequent incorporation of Glu was accomplished via ion exchange
  • The PEDOT/Glu-coated electrode showed better cell attachment compared with a PEDOT/TSNa-coated electrode in in vitro cell culture of PC12
  • The stability of PEDOT was studied by immersing the coated electrode in a biologically relevant reducing agent of glutathione

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