Genetic determinants of bone mass in adult women: A reevaluation of the twin model and the potential importance of gene interaction on heritability estimates

We estimated genetic effects on bone density in pre‐ and postmenopausal twins and critically considered the assumptions of the twin model

Charles W. Slemenda

2010

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Scholarcy highlights

  • We estimated genetic effects on bone density in pre‐ and postmenopausal twins and critically considered the assumptions of the twin model
  • Bone mass in the radius, lumbar spine, and hip, anthropometric measurements, usual calcium and caffeine intake, tobacco and alcohol use, number of pregnancies and live births, menstrual history, usual physical activity, and medical history were measured in a volunteer sample of 171 twin pairs, aged 25–80, free of diseases known to affect bone mass or mineral metabolism
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