Highly Fluorescent Nanodiamonds Protein-Functionalized for Cell Labeling and Targeting

Fluorescent nanodiamond is attracting much attention as a bioimaging agent because of its inherent biocompatibility and superior optical properties

Be-Ming Chang

2013

Scholarcy highlights

  • Fluorescent nanodiamond is attracting much attention as a bioimaging agent because of its inherent biocompatibility and superior optical properties
  • It is shown that the 100‐nm FND particles fabricated by using nitrogen‐rich type Ib diamonds and high‐energy proton irradiation are highly fluorescent and readily functionalizable with proteins for biological applications
  • High targeting specificity of the bioconjugated FND is demonstrated with the human hepatoma cell line, HepG2, and breast cancer cell lines, ASB145‐1R, MCF‐7, and MDA‐MB‐231 cells
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