Blood–Brain Barrier

The blood–brain barrier consists of endothelial cells lining brain capillaries

Darryl R Peterson

2013

Scholarcy highlights

  • The blood–brain barrier consists of endothelial cells lining brain capillaries
  • It serves to restrict and control the movement of substances between the general circulation and brain extracellular fluid. It participates in regulating the volume and composition of fluid surrounding the brain through specific transport processes, and contributes to homoeostasis of the central nervous system
  • Administered drugs intended to treat neurological disorders must be designed to bypass the restrictive elements of the blood–brain barrier
  • Pathological conditions associated with the central nervous system may alter blood–brain barrier function

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