Treatments for symptomatic urinary tract infections during pregnancy

We considered all trials where the intention was to allocate participants randomly to one of at least two alternative treatments for any symptomatic urinary tract infection

Juan C Vazquez

2011

Scholarcy highlights

  • Urinary tract infections, including pyelonephritis, are serious complications that may lead to significant maternal and neonatal morbidity and mortality
  • We considered all trials where the intention was to allocate participants randomly to one of at least two alternative treatments for any symptomatic urinary tract infection
  • Antibiotic treatment is effective for the cure of urinary tract infections, there are insufficient data to recommend any specific drug regimen for treatment of symptomatic urinary tract infections during pregnancy
  • All the antibiotics studied were shown to be very effective in decreasing the incidence of the different outcomes
  • Urinary tract infections have been classified as asymptomatic bacteriuria, cystitis and pyelonephritis
  • Gestational age at birth was greater in women from the outpatient group), while birthweight was
  • From the best available evidence from randomised controlled trials, which treatment is most effective for symptomatic UTIs during pregnancy in terms of cure rates, recurrent infection, preterm delivery, premature rupture of membranes, admission to neonatal intensive care unit, need for change of antibiotic and incidence of prolonged pyrexia
  • It is reasonable to give the simplest and cheapest available treatment and consider giving it to women who will be compliant on an outpatient basis, considering how disruptive it is for a pregnant woman and her family when she is hospitalised

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