Treatments for symptomatic urinary tract infections during pregnancy

We considered all trials where the intention was to allocate participants randomly to one of at least two alternative treatments for any symptomatic urinary tract infection

Juan C Vazquez; Edgardo Abalos

2011

Scholarcy highlights

  • Urinary tract infections, including pyelonephritis, are serious complications that may lead to significant maternal and neonatal morbidity and mortality
  • We considered all trials where the intention was to allocate participants randomly to one of at least two alternative treatments for any symptomatic urinary tract infection
  • Urinary tract infections may lead to serious maternal complications such as septic shock, respiratory insu iciency, fluid balance disorders, chronic renal insu iciency and death
  • UTIs have been classified as asymptomatic bacteriuria, cystitis and pyelonephritis
  • The frequency of asymptomatic bacteriuria during pregnancy has been reported to be between 2% to 10%
  • We re-analysed data using the random-e ects model, but results did not change significantly
  • In order to gather more information on comparative e icacy of di erent antibiotics used for symptomatic UTIs, we performed a search of trials and reviews including non-pregnant women
  • It is reasonable to give the simplest and cheapest available treatment and consider giving it to women who will be compliant on an outpatient basis, considering how disruptive it is for a pregnant woman and her family when she is hospitalised

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