An Intensive Behavioral Weight Loss Intervention and Hot Flushes in Women<alt-title>Weight Loss Intervention and Hot Flushes</alt-title>
We examined whether changes in weight, body mass index, abdominal circumference, physical activity, calorie intake, blood pressure, and overall physical or mental functioning were associated with improvement in bothersome hot flushes in this population
Higher body mass index is associated with worse hot flushes during menopause but the effect of weight loss on flushing is unclear
The intervention was associated with greater improvement in bothersome flushes vs control
Reductions in weight, body mass index, and abdominal circumference were each associated with improvement in flushing, but changes in physical activity, calorie intake, blood pressure, and physical and mental functioning were not related
Among women who were overweight or obese and had bothersome hot flushes, an intensive behavioral weight loss intervention resulted in improvement in flushing relative to control
We examined whether changes in weight, body mass index, abdominal circumference, physical activity, calorie intake, blood pressure, and overall physical or mental functioning were associated with improvement in bothersome hot flushes in this population
The effect of the intensive intervention on bothersome hot flushes was modestly decreased and no longer statistically significant after adjustment for improvement in weight
In aggregate analyses of all women reporting bothersome hot flushes at baseline, decrease in weight, decrease in BMI, and decrease in abdominal circumference were each associated with improvement in selfreported hot flushes during 6 months
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